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Tribe Clinical Research and Greenville Ear, Nose and Throat (ENT) Announce First Clinical Research Partnership Phase 3 study expands access to investigational treatment options for adults living with chronic rhinosinusitis with nasal polyps

GREENVILLE, S.C. — [10.21.26] — Tribe Clinical Research (TCR) is pleased to announce the launch of its first clinical research study in partnership with Greenville Ear, Nose and Throat (ENT), marking an important milestone in the organizations' shared commitment to expanding access to clinical research opportunities across the Upstate.

The Phase 3 clinical trial will evaluate the efficacy and safety of an investigational medication for adults living with chronic rhinosinusitis with nasal polyps (CRSwNP), a persistent inflammatory condition that can significantly affect breathing, sleep, sense of smell, and overall quality of life.

"This partnership with Greenville ENT is an exciting step forward in our mission to bring clinical research opportunities closer to patients and the physicians they already know and trust," said Jennifer Lehman, CEO of Tribe Clinical Research. "Together, we can connect more people with potential new treatment options while helping advance the future of medicine."

Adults ages 18 and older may be eligible to participate if they have been diagnosed with chronic rhinosinusitis with nasal polyps for at least 12 months and have experienced symptoms for at least 12 weeks before screening. Additional eligibility criteria apply.

"Patients with severe nasal polyps can be a challenging population to treat. Standard non-surgical treatments are often ineffective, and many of these patients have endured multiple surgeries over many years to control their symptoms," said Dr. William Frazier of Greenville ENT. "Greenville ENT is excited to offer this clinical trial evaluating a novel therapy that represents a new treatment approach for the management of these patients."

The study will be conducted at the Tribe Clinical Research Greenville location. Qualified participants will receive study-related care at no cost and may receive up to $6,555 in compensation for time and travel.

About Greenville ENT

Greenville ENT provides comprehensive ear, nose, and throat care for patients of all ages across a wide range of conditions. Its team of ENT specialists is committed to

making better hearing, easier breathing, and healthier living more accessible through compassionate, patient-centered care.

About Tribe Clinical Research

Tribe Clinical Research TM (TCR) is a South Carolina-based clinical research organization founded in 2020. Specializing in both adult and pediatric trials, TCR is committed to advancing medicine by combining clinical excellence with the highest research standards.

Driven by a mission to bring hope to patients who need it most, TCR partners with healthcare providers and industry sponsors to conduct trials across a wide range of therapeutic areas. With a deep commitment to community, patient outcomes, and innovation, Tribe Clinical Research is building a future where research and care go hand in hand.

Together we can make a difference, because advancing medicine takes more than a single person or practice—it takes a Tribe.

For more information, visit TribeClinicalResearch.com and follow us on:

Media Contact:
Jennifer Lehman, RPh, PharmD
CEO, Tribe Clinical Research
info@tribeclinicalresearch.com
(864)334-0141

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